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https://www.medias-presse.info/57-personnalites-scientifiques-et-medicales-internationales-expliquent-pourquoi-il-faut-larret-immediat-de-toutes-les-vaccinations-anti-covid/142464/
57 leading scientists and doctors explain why all COVID vaccinations must be stopped immediately
France Soir reveals that a group of 57 leading scientists, doctors and political experts published a report questioning the safety and effectiveness of the current COVID-19 “vaccines” and calling
for an immediate end to all vaccination programs.
The therapies used as "vaccines" do not match the definition of the word vaccine and would more appropriately be referred to as gene therapies or vaccine vector therapies.
There are two certainties about the worldwide prevalence of these Covid-19 therapies:
This manuscript can be read in the pre-print below. It was prepared by nearly sixty doctors, scientists and public order experts from around the world and should be urgently addressed to world leaders, as well as to everyone involved in the production and distribution of the various Covid-19 vaccines in circulation. be transmitted.
In addition, there are still a number of unanswered questions about the safety, effectiveness and necessity of these Covid-19 therapies.
This study is a bang and should be read by anyone, regardless of their views on gene therapy or vaccines. Not enough citizens are asking critical questions about this. Most people simply obey the orders of their governments as if they deserve their full trust. However, this is not the case. This manuscript is a step forward in accountability and the free flow of information on this important topic. Please take the time to read and spread the word.
Mass Vaccination Against SARS-CoV-2:
Urgent Vaccine Safety Questions That Need To Be Answered By International Health Authorities, Regulators, Governments, And Vaccine Developers
Authors: Roxana Bruno (1), Peter McCullough (2), Teresa Forcades i Vila (3), Alexandra Henrion-Caude (4), Teresa García-Gasca (5), Galina P. Zaitzeva (6), Sally Priester (7 ), María J. Martínez Albarracín (8), Alejandro Sousa-Escandon (9), Fernando López Mirones (10), Bartomeu Payeras Cifre (11), Almudena Zaragoza Velilla (10), Leopoldo M. Borini () 1, Mario Mas (1), Ramiro Salazar (1), Edgardo Schinder (1), Eduardo A Yahbes (1), Marcela Witt (1), Mariana Salmeron (1), Patricia Fernández (1), Miriam M. Marchesini (1), Alberto J. Kajihara (1), Marisol V. de la Riva (1), Patricia J. Chimeno (1), Paola A. Grellet (1), Matelda Lisdero (1), Pamela Mas (1), Abelardo J. Gatica Baudo (12), Elisabeth Retamoza (12), Oscar Botta (13), Chinda C. Brandolino (13), Javier Sciuto (14), Mario Cabrera Avivar (14),Mauricio Castillo (15), Patricio Villarroel (15), Emilia P. Poblete Rojas (15), Bárbara Aguayo (15), Dan I. Macías Flores (15), Jose V. Rossell (16), Julio C. Sarmiento (17 ), Victor Andrade-Sotomayor (17), Wilfredo R. Stokes Baltazar (18), Virna Cedeño Escobar (19), Ulises Arrúa (20), Atilio Farina del Río (21), Tatiana Campos Esquivel (22), Patricia Callisperis ( 23), María Eugenia Barrientos (24), Karina Acevedo-WhitehouseKarina Acevedo-WhitehouseKarina Acevedo-Whitehouse
Preface
Since the beginning of the COVID-19 epidemic, an unprecedented race to test new platforms designed to confer immunity against SARS-CoV-2 has broken out, leading to the emergency approval of various vaccines. Despite advances in early multidrug-resistant therapy for COVID-19 patients, the current mission is to vaccinate the world's population as soon as possible. The lack of extensive animal testing prior to clinical trials and approval based on safety data obtained in studies lasting less than 3.5 months raises questions about the safety of these vaccines. The recently identified role of the SARS-CoV-2 spike glycoprotein in inducing the endothelial damage characteristic of COVID-19, even in the absence of infection, is highly relevant as most approved vaccines induce the production of spike glycoproteins in recipients. Given the high rate of adverse event occurrences and the wide range of types of adverse events reported to date, as well as the potential for vaccine-induced disease aggravation, Th2 immunopathology, autoimmunity and immune evasion, there is a need for a better understanding of the benefits and risks of mass vaccination, in particular in groups excluded from clinical trials. Despite calls for caution, the risks of vaccination against SARS-CoV-2 have been downplayed or ignored by health organizations and government agencies.
introduction
Since the Covid-19 pandemic was proclaimed in March 2020, more than 150 million cases and 3 million deaths have been reported worldwide. Despite the advances in early outpatient multi-drug resistant therapy for high-risk patients, which has led to an 85 percent reduction in Covid-19-related hospital stays and deaths [1], the current control paradigm is mass vaccination. While we acknowledge the effort involved in developing, manufacturing, and emergency licensing SARS-CoV-2 vaccines, we are concerned that the risks have been minimized or ignored by health organizations and government agencies, despite caution [2– 8th].
Vaccines against other coronaviruses have never been approved for humans, and the data gained in the development of coronavirus vaccines that are designed to elicit neutralizing antibodies show that they can treat COVID-19 disease through antibody-dependent enhancement (ADE ) and Th2 immunopathology can worsen regardless of vaccine. Platform and delivery method [9–11]. It is known that in animals vaccinated against SARS-CoV and MERS-CoV, after a viral challenge, an exacerbation of the disease occurs, which is attributed to immune complexes and the Fc-mediated uptake of the virus by macrophages that cause the T Increase cell activation and inflammation [11 13].
In March 2020, vaccine immunologists and coronavirus experts assessed the risks of the SARS-CoV-2 vaccine based on SARS-CoV vaccine trials in animal models. The panel concluded that undesirable side effects and immunopathology were a real problem, but stated that their risk was insufficient to delay clinical trials, although continuous monitoring would be required [14]. Although there is no clear evidence of the occurrence of ADRs and vaccine-related immunopathology in test subjects who were immunized with SARS-CoV-2 vaccines [15], these serious adverse events (SAEs) have not been specifically investigated in previous safety studies. Given the fact Since the follow-up of the subjects did not last longer than 2–3.5 months after the second dose [16–19], it is unlikely that such an SAE was observed. Despite 92 reporting errors, it cannot be overlooked that even taking into account the number of vaccines administered, according to the US Vaccine Adverse Event Reporting System (VAERS), the number of deaths per million vaccine doses administered has increased more than ten-fold. We believe that there is an urgent need for an open scientific dialogue on vaccine safety in the context of large-scale vaccination. that even considering the number of vaccines administered, according to the US Vaccine Adverse Event Reporting System (VAERS), the number of deaths per million vaccine doses administered has increased more than ten-fold. We believe that there is an urgent need for an open scientific dialogue on vaccine safety in the context of large-scale vaccination. that even considering the number of vaccines administered, according to the US Vaccine Adverse Event Reporting System (VAERS), the number of deaths per million vaccine doses administered has increased more than ten-fold. We believe that there is an urgent need for an open scientific dialogue on vaccine safety in the context of large-scale vaccination.
In this article, we describe some of the risks of mass vaccination related to exclusion criteria for Phase 3 trials and discuss the GSSs reported in national and regional adverse event registration systems. We point out unanswered questions and draw attention to the need for a more cautious approach to mass vaccination. We believe that there is an urgent need for an open scientific dialogue on vaccine safety in the context of large-scale vaccination.
Exclusion criteria for the phase 3 study SARS-CoV-2
With a few exceptions, the SARS-CoV-2 vaccine studies have excluded the elderly [16–19], making it impossible to identify post-vaccination post-vaccination post-vaccination post-vaccination post-vaccination inflammation in the elderly of eosinophilia and increased inflammation, the occurrence of eosinophilia and increased inflammation in the elderly have been excluded. Studies with SARS-CoV vaccines have shown that immunized older mice have a particularly high risk of potentially fatal Th2 immunopathology [9,20]. Despite these findings and the extremely limited data on the safety and effectiveness of SARS-CoV-2 vaccines in the elderly, mass vaccination campaigns have focused on this age group from the start. Most studies also included pregnant and breastfeeding subjects, as well as people with chronic and serious illnesses such as tuberculosis, hepatitis C, autoimmunity, coagulopathies,
Another exclusion criterion in almost all studies was previous exposure to SARS-CoV-2. This is unfortunate because it has eliminated the possibility of obtaining highly relevant information about post-vaccination adverse events in people who already have anti-SARS-Cov-2 antibodies. To the best of our knowledge, ADEs are not routinely monitored for any age or disease group currently receiving the vaccine. In addition, although a significant portion of the population already has antibodies [21], testing for anti-SARS-CoV-2 antibody status prior to vaccine administration is not routinely performed.
Do Serious Adverse Events With SARS-CoV-2 Vaccines Go Undetected?
COVID-19 covers a broad clinical spectrum, ranging from very mild to severe pulmonary pathology to fatal multi-organ diseases with inflammatory, cardiovascular and / or blood clotting dysregulations [22–24]. In this sense, vaccine-related ADR or immunopathology could not be clinically differentiated from severe COVID-19 [25]. In addition, the spike glycoprotein alone, even in the absence of the SARS-CoV-2 virus, causes endothelial damage and high blood pressure in Syrian hamsters in vitro and in vivo by downregulating the angiotensin-converting enzyme 2 (ACE2) and changing mitochondrial function [ 26]. Although these results have yet to be confirmed in humans, the implications of this finding are staggering, as all vaccines approved for emergency use are based on the administration or induction of spike glycoprotein synthesis. In the case of mRNA and adenovirus vaccines, the duration of spike production in humans after vaccination has not been investigated in any study.
It should be borne in mind that vaccine-induced spike synthesis may cause clinical signs of severe COVID-19 infection and could be mistakenly counted as new cases of SARS-CoV-2 infection. If so, the real negative effects of the current global vaccination strategy may never be realized unless studies specifically investigate this issue. There is already non-causal evidence of a temporary or sustained increase in deaths from COVID-19 after vaccination in some countries (Fig. 1). Given the spike pathogenicity, these deaths must be carefully investigated to determine if they are vaccine-related. No studies have looked at the duration of spike production in humans after vaccination.
Unexpected adverse reactions to SARS-CoV-2 vaccines
Autoimmunity is another critical issue to consider given the global scale of SARS-CoV-2 vaccination. SARS-CoV 2 has many immunogenic proteins, and all but one have similarities to human proteins [27]. These can serve as a source of antigens, which leads to autoimmunity [28]. While it is true that the same effects could be observed with a natural infection with SARS-CoV-2, the vaccination is intended for the majority of the world's population, while it is estimated that only 10% of the world's population are infected with SARS-CoV-2, according to this Dr. Michael Ryan, director of the World Health Organization's emergency department. We couldn't find any evidence
Some adverse events, including bleeding disorders, have been reported in healthy young vaccinees. These cases have resulted in the suspension or discontinuation of the use of ChAdOx1-nCov-19 and adenoviral vectorized vaccines by Janssen in some countries. It has now been suggested that vaccination with ChAdOx1-nCov-19 can lead to immune thrombotic thrombocytopenia (ITT), which is mediated by platelet-activating antibodies against platelet factor 4 and clinically mimics heparin-induced autoimmune thrombocytopenia [29]. Unfortunately, the risk was overlooked in approving these vaccines, although adenovirus-induced thrombocytopenia has been known for more than a decade and is a consistent event with adenoviral vectors [30]. The risk of TTIV is likely to be higher in people who are already at risk for blood clots.
Vaccine-related effects can also occur at the population level. SARS-CoV 2 is a rapidly developing RNA virus that has so far produced more than 40,000 variants [32,33], some of which affect the antigenic domain of the spike glycoprotein [34,35]. In view of the high mutation rates, the vaccine-induced synthesis of high levels of anti-SARS-CoV-2 spike antibodies in vaccinated people could theoretically lead to suboptimal reactions to subsequent infections with other variants [36], a phenomenon known as "Sin" [37 ] or antigenic priming [38] is known. The extent to which mutations affecting the antigenicity of SARS-CoV-2 are fixed during viral evolution is unknown [39], but it is conceivable that vaccines may act as selective forces, which lead to variants with higher infectivity or transmissibility. Given the high similarity between the known SARS-CoV-2 variants, this scenario is unlikely [32,34], but if future variants should differ further in key epitopes, the global vaccination strategy may have helped shape an even more dangerous virus. The WHO was recently made aware of this risk in the form of an open letter [40]. to shape an even more dangerous virus. The WHO was recently made aware of this risk in the form of an open letter [40]. to shape an even more dangerous virus. The WHO was recently made aware of this risk in the form of an open letter [40].
discussion
The risks described here represent a major obstacle to the continuation of the global vaccination against SARS-CoV-2. The safety of all SARS-CoV-2 vaccines must be proven before more people are exposed to the risk of these experiments than the release of one Vaccine candidates without time to fully understand the resulting health implications could exacerbate the current global crisis. [41]. Risk stratification of the vaccinated is essential. According to the UK government, people under the age of 60 have an extremely low risk of dying from COVID-19. However, according to Eudravigillance, most serious adverse events after SARS-CoV-2 vaccination occur in people aged 18–64 years. Of particular concern is the planned vaccination schedule for children 6 years and older in the US and UK. Dr. Anthony Fauci recently forecast that teenagers across the country will be vaccinated in the fall and younger children in the spring of 2022. Lee UK is waiting for study results to begin vaccinating 11 million children under the age of 18 with the experimental vaccines as they have a 99.997% survival rate when infected with SARS-CoV 2, according to the Centers for Disease Control and Prevention are. Not only is COVID-19 irrelevant as a threat to this age group, there is also no reliable evidence which demonstrate the effectiveness or effectiveness of the vaccine in this population group or exclude harmful side effects of these experimental vaccines. With this in mind, as doctors advise patients to administer COVID-19 electively, there is a great need to better understand the benefits and risks of administration, especially in studied groups.
In summary, in connection with the emergency approval of the use of SARS-CoV-2 vaccines and the current gaps in our understanding of their safety, the following questions must be asked:
- Is it known whether cross-reacting antibodies from previous coronavirus infections or vaccine-induced antibodies can influence the risk of unintended pathogenesis after vaccination with
COVID-19?
Against the background of these concerns, we propose to stop mass vaccination and to open an urgent, pluralistic, critical and scientifically based dialogue on vaccination against SARS-CoV-2 between scientists, doctors, international health agencies, regulators, governments and vaccine developers. This is the only way to bridge the current gap between scientific knowledge and public health policy regarding SARS-CoV-2 vaccines. We believe that humanity deserves a deeper understanding of the risks than what is currently presented as an official position. An open scientific dialogue is urgently needed to avoid the erosion of public trust in science and public health; and to ensure that WHO and national health authorities protect the interests of humanity during the current pandemic. There is an urgent need to move public health policy back towards evidence-based medicine, based on a careful assessment of relevant scientific research. It is imperative to follow science. return public health policy to evidence-based medicine based on careful assessment of relevant scientific research. It is imperative to follow science. return public health policy to evidence-based medicine based on careful assessment of relevant scientific research. It is imperative to follow science.
1 www.gov.uk/government/publications/covid-19-reported-sars-cov-2-deaths-in-england/covid-19-confirmed-deaths-in-england-report
Conflict of Interest Statement
The authors state that the research was conducted in the absence of any commercial or financial relationship that could be construed as a potential conflict of interest.
credentials
Captions
Figure 1: Number of new deaths from COVID-19 versus number of people who received at least one vaccine dose for selected countries. The graph shows data from the start of vaccination through May 3, 365, 2021. A) India (9.25% of the vaccinated population), B) Thailand (1.58% of the vaccinated population), C) Colombia (6.79 % of the vaccinated population), D) Mongolia (31.65% of the vaccinated population), E) Israel (62.47% of the vaccinated population), F) worldwide (7.81% of the vaccinated population). The charts were created using data from Our World in Data (accessed May 4, 2021) at github.com/owid/covid–19–données/arbre/maître/public/données/vaccinations
Affiliations *
1. Epidemiólogos Argentinos Metadisciplinarios. República Argentina.
2. Baylor University Medical Center. Dallas, Texas, USA.
3. Monestir de Sant Benet de Montserrat, Montserrat, Spain
4. INSERM U781 Hôpital Necker-Enfants Malades, Université Paris Descartes-Sorbonne Cité,
Institut Imagine, Paris, France.
5. Science School. Autonomous University of Querétaro, Querétaro, Mexico.
6. Retired Professor of Medical Immunology. Universidad de Guadalajara, Jalisco, Mexico.
7. Médicos por la Verdad Puerto Rico. Ashford Medical Center. San Juan, Puerto Rico.
8. Retired Professor of Clinical Diagnostic Techniques. University of Murcia, Murcia, Spain
9. Urologist, Comarcal de Monforte Hospital, University of Santiago de Compostela, Spain.
10. Biólogos por la Verdad, Spain.
11. retired biologist. University of Barcelona. Specialized in microbiology. Barcelona, Spain.
12. Center for Integrative Medicine MICAEL (Medicina Integrativa Centro Antroposófico Educando
en Libertad). Mendoza, Argentine Republic.
13. Médicos por la Verdad Argentina. República Argentina.
14. Médicos por la Verdad Uruguay. República Oriental del Uruguay.
15. Médicos por la Libertad Chile. Republic of Chile.
16. doctor, orthopedist. Republic of Chile.
17. Médicos por la Verdad Perú. República del Perú.
18. Medicos por la Verdad Guatemala. Republic of Guatemala.
19. Concepto Azul SA Ecuador.
20. Médicos por la Verdad Brasil. Brazil.
21. Médicos por la Verdad Paraguay.
22. Médicos por la Verdad Costa Rica.
23. Médicos por la Verdad Bolivia.
24. Médicos por la Verdad El Salvador.
* Correspondence: Karina Acevedo-Whitehouse, karina.acevedo.whitehouse@uaq.mx